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Computational epitope map of SARS-CoV-2 spike protein

The primary immunological target of COVID-19 vaccines is the SARS-CoV-2 spike (S) protein. S is exposed on the viral surface and mediates viral entry into the host cell. To identify possible antibody binding sites, we performed multi-microsecond molecular dynamics simulations of a 4.1 million atom s...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Sikora, Mateusz, von Bülow, Sören, Blanc, Florian E. C., Gecht, Michael, Covino, Roberto, Hummer, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016105/
https://ncbi.nlm.nih.gov/pubmed/33793546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008790
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