Diastereomeric Cyclopentane-Based Maltosides (CPMs) as Tools for Membrane Protein Study

Amphiphilic agents, called detergents, are invaluable tools for studying membrane proteins. However, membrane proteins encapsulated by conventional head-to-tail detergents tend to denature or aggregate, necessitating the development of structurally distinct molecules with improved efficacy. Here, a...

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Pubblicato in:J Am Chem Soc
Autori principali: Das, Manabendra, Mahler, Florian, Hariharan, Parameswaran, Wang, Haoqing, Du, Yang, Mortensen, Jonas S., Patallo, Eugenio Pérez, Ghani, Lubna, Glück, David, Lee, Ho Jin, Byrne, Bernadette, Loland, Claus J., Guan, Lan, Kobilka, Brian K., Keller, Sandro, Chae, Pil Seok
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015409/
https://ncbi.nlm.nih.gov/pubmed/33315387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c09629
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