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DROSHA is recruited to DNA damage sites by the MRN complex to promote non-homologous end joining
The DNA damage response (DDR) is the signaling cascade that recognizes DNA double-strand breaks (DSBs) and promotes their resolution via the DNA repair pathways of non-homologous end joining (NHEJ) or homologous recombination (HR). We and others have shown that DDR activation requires DROSHA; howeve...
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| Udgivet i: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists Ltd
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8015226/ https://ncbi.nlm.nih.gov/pubmed/33558311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.249706 |
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