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OX40 as a novel target for the reversal of immune escape in colorectal cancer

First-generation immunological checkpoint inhibitors, such as CTLA-4, PD-L1 and PD-1 exhibit significant advantages over conventional cytotoxic drugs, such as oxaliplatin and 5-FU, for the treatment of colorectal cancer. However, these inhibitors are not ideal due to their low objective response rat...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Yan, Lin-Hai, Liu, Xiao-Liang, Mo, Si-Si, Zhang, Di, Mo, Xian-Wei, Tang, Wei-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8014382/
https://ncbi.nlm.nih.gov/pubmed/33841630
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