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New insights on OX40 in the control of T cell immunity and immune tolerance in vivo
OX40 is a T cell costimulatory molecule that belongs to the TNFR superfamily. In the absence of immune activation, OX40 is selectively expressed by Foxp3(+) Tregs, but not by resting conventional T cells. The exact role of OX40 in Treg homeostasis and function remains incompletely defined. Here, we...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3262989/ https://ncbi.nlm.nih.gov/pubmed/22147766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101373 |
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