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New insights on OX40 in the control of T cell immunity and immune tolerance in vivo

OX40 is a T cell costimulatory molecule that belongs to the TNFR superfamily. In the absence of immune activation, OX40 is selectively expressed by Foxp3(+) Tregs, but not by resting conventional T cells. The exact role of OX40 in Treg homeostasis and function remains incompletely defined. Here, we...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Xiao, Xiang, Gong, Weihua, Demirci, Gulcin, Liu, Wentao, Spoerl, Silvia, Chu, Xiufeng, Bishop, D. Keith, Turka, Laurence A., Li, Xian C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262989/
https://ncbi.nlm.nih.gov/pubmed/22147766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101373
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