Design and High Expression of Non-glycosylated Lysostaphins in Pichia pastoris and Their Pharmacodynamic Study

Lysostaphin is an effective antimicrobial agent to Staphylococcus, especially for the methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Staphylococcus aureus (MDRSA). In this study, the seven lysostaphin derived mutants (rLys) were designed to overcome the barrier of glycosy...

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Dades bibliogràfiques
Publicat a:Front Microbiol
Autors principals: Shen, Wenluan, Yang, Na, Teng, Da, Hao, Ya, Ma, Xuanxuan, Mao, Ruoyu, Wang, Jianhua
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012855/
https://ncbi.nlm.nih.gov/pubmed/33815324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.637662
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