Inhibition of PKCε induces primordial germ cell reprogramming into pluripotency by HIF1&2 upregulation and histone acetylation

Historically, primordial germ cells (PGCs) have been a good model to study pluripotency. Despite their low numbers and limited accessibility in the mouse embryo, they can be easily and rapidly reprogrammed at high efficiency with external physicochemical factors and do not require transcription fact...

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Publicat a:Am J Stem Cells
Autors principals: Moratilla, Adrian, Sainz de la Maza, Diego, Cadenas Martin, Marta, López-Iglesias, Pilar, González-Peramato, Pilar, De Miguel, Maria P
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2021
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012778/
https://ncbi.nlm.nih.gov/pubmed/33815934
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