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Colonisation of the colonic mucus gel layer with butyrogenic and hydrogenotropic bacteria in health and ulcerative colitis

Butyrate is the primary energy source for colonocytes and is essential for mucosal integrity and repair. Butyrate deficiency as a result of colonic dysbiosis is a putative factor in ulcerative colitis (UC). Commensal microbes are butyrogenic, while others may inhibit butyrate, through hydrogenotropi...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Earley, Helen, Lennon, Grainne, Coffey, J. Calvin, Winter, Desmond C., O’Connell, P. Ronan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012382/
https://ncbi.nlm.nih.gov/pubmed/33790336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86166-6
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