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The abundance of Akkermansia muciniphila and its relationship with sulphated colonic mucins in health and ulcerative colitis

Akkermansia muciniphila utilises colonic mucin as its substrate. Abundance is reduced in ulcerative colitis (UC), as is the relative proportion of sulphated mucin in the mucus gel layer (MGL). It is unknown if these phenomena are related, however reduced sulphated mucins could contribute to reduced...

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Опубликовано в: :Sci Rep
Главные авторы: Earley, Helen, Lennon, Grainne, Balfe, Áine, Coffey, J. Calvin, Winter, Desmond C., O’Connell, P. Ronan
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821857/
https://ncbi.nlm.nih.gov/pubmed/31666581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51878-3
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