Influences of the colonic microbiome on the mucous gel layer in ulcerative colitis

The colonic mucus gel layer (MGL) is a critical component of the innate immune system acting as a physical barrier to microbes, luminal insults, and toxins. Mucins are the major component of the MGL. Selected microbes have the potential to interact with, bind to, and metabolize mucins. The tolerance...

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Bibliographic Details
Main Authors: Lennon, Gráinne, Balfe, Áine, Earley, Helen, Devane, Liam A, Lavelle, Aonghus, Winter, Desmond C, Coffey, J Calvin, O'Connell, P Ronan
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153764/
https://ncbi.nlm.nih.gov/pubmed/24714392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.28793
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