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NMDAR-independent, cAMP-dependent antidepressant actions of ketamine

Ketamine produces rapid and robust antidepressant effects in depressed patients within hours of administration, often when traditional antidepressant compounds have failed to alleviate symptoms. We hypothesized that ketamine would translocate Gα(s) from lipid rafts to non-raft microdomains, similarl...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Wray, Nathan H., Schappi, Jeffrey M., Singh, Harinder, Senese, Nicolas B., Rasenick, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011999/
https://ncbi.nlm.nih.gov/pubmed/29895894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0083-8
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