Identification, Structure–Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators

[Image: see text] Cystic fibrosis (CF) is a life-threatening autosomal recessive disease, caused by mutations in the CF transmembrane conductance regulator (CFTR) chloride channel. CFTR modulators have been reported to address the basic defects associated with CF-causing mutations, partially restori...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Med Chem
Päätekijät: Brindani, Nicoletta, Gianotti, Ambra, Giovani, Simone, Giacomina, Francesca, Di Fruscia, Paolo, Sorana, Federico, Bertozzi, Sine Mandrup, Ottonello, Giuliana, Goldoni, Luca, Penna, Ilaria, Russo, Debora, Summa, Maria, Bertorelli, Rosalia, Ferrera, Loretta, Pesce, Emanuela, Sondo, Elvira, Galietta, Luis J. V., Bandiera, Tiziano, Pedemonte, Nicoletta, Bertozzi, Fabio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2020
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011931/
https://ncbi.nlm.nih.gov/pubmed/32946228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c01050
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia