Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1–13)-NH(2)

[Image: see text] Nociceptin/orphanin FQ (N/OFQ) controls different biological functions via selective stimulation of the N/OFQ peptide (NOP) receptor. The pleiotropic actions of N/OFQ may limit the development of NOP ligands as innovative drugs in different therapeutic areas. The pharmacological co...

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Publicat a:J Med Chem
Autors principals: Pacifico, Salvatore, Ferrari, Federica, Albanese, Valentina, Marzola, Erika, Neto, Joaquim Azevedo, Ruzza, Chiara, Calò, Girolamo, Preti, Delia, Guerrini, Remo
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011926/
https://ncbi.nlm.nih.gov/pubmed/32901477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.9b02057
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