An elevated polyclonal free light chain level reflects a strong interferon signature in patients with systemic autoimmune diseases

High amount of polyclonal free light chains (FLC) are reported in systemic autoimmune diseases (SAD) and we took advantage of the PRECISESADS study to better characterize them. Serum FLC levels were explored in 1979 patients with SAD (RA, SLE, SjS, Scl, APS, UCTD, MCTD) and 614 healthy controls. Inf...

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Udgivet i:J Transl Autoimmun
Main Authors: Bettacchioli, Eléonore, Le Gaffric, Christelle, Mazeas, Margaux, Borghi, Maria Orietta, Frostegard, Johan, Barturen, Guillermo, Makowska, Zuzanna, Babei, Sepideh, Lesche, Ralf, Meroni, Pier Luigi, Alarcon-Riquelme, Marta E., Renaudineau, Yves
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Research paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010703/
https://ncbi.nlm.nih.gov/pubmed/33817614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtauto.2021.100090
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