An elevated polyclonal free light chain level reflects a strong interferon signature in patients with systemic autoimmune diseases

High amount of polyclonal free light chains (FLC) are reported in systemic autoimmune diseases (SAD) and we took advantage of the PRECISESADS study to better characterize them. Serum FLC levels were explored in 1979 patients with SAD (RA, SLE, SjS, Scl, APS, UCTD, MCTD) and 614 healthy controls. Inf...

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Dettagli Bibliografici
Pubblicato in:J Transl Autoimmun
Autori principali: Bettacchioli, Eléonore, Le Gaffric, Christelle, Mazeas, Margaux, Borghi, Maria Orietta, Frostegard, Johan, Barturen, Guillermo, Makowska, Zuzanna, Babei, Sepideh, Lesche, Ralf, Meroni, Pier Luigi, Alarcon-Riquelme, Marta E., Renaudineau, Yves
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Research paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010703/
https://ncbi.nlm.nih.gov/pubmed/33817614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtauto.2021.100090
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