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Anti-AAV Antibodies in AAV Gene Therapy: Current Challenges and Possible Solutions
Adeno-associated virus (AAV) vector-based gene therapy is currently the only in vivo gene therapy approved in the US and Europe. The recent tragic death of three children in a clinical trial to treat X-Linked Myotubular Myopathy by delivering myotubularin with an AAV8 vector notwithstanding, AAV rem...
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| Pubblicato in: | Front Immunol |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8010240/ https://ncbi.nlm.nih.gov/pubmed/33815421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.658399 |
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