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Successful Transduction with AAV Vectors after Selective Depletion of Anti-AAV Antibodies by Immunoadsorption

Gene therapy with adeno-associated virus (AAV)-based vectors shows great promise for the gene therapeutic treatment of a broad array of diseases. In fact, the treatment of genetic diseases with AAV vectors is currently the only in vivo gene therapy approach that is approved by the US Food and Drug A...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Orlowski, Alejandro, Katz, Michael G., Gubara, Sarah M., Fargnoli, Anthony S., Fish, Kenneth M., Weber, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011017/
https://ncbi.nlm.nih.gov/pubmed/32055647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.01.004
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