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A Metabolic Reprogramming of Glycolysis and Glutamine Metabolism Is a Requisite for Renal Fibrogenesis—Why and How?

Chronic Kidney Disease (CKD) is characterized by organ remodeling and fibrosis due to failed wound repair after on-going or severe injury. Key to this process is the continued activation and presence of matrix-producing renal fibroblasts. In cancer, metabolic alterations help cells to acquire and ma...

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Vydáno v:Front Physiol
Hlavní autoři: Hewitson, Timothy D., Smith, Edward R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010236/
https://ncbi.nlm.nih.gov/pubmed/33815149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.645857
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