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Metabolic reprogramming of glycolysis and glutamine metabolism are key events in myofibroblast transition in systemic sclerosis pathogenesis

Systemic Sclerosis (SSc) is a rare fibrotic autoimmune disorder for which no curative treatments currently exist. Metabolic remodelling has recently been implicated in other autoimmune diseases; however, its potential role in SSc has received little attention. Here, we aimed to determine whether cha...

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Henderson, John, Duffy, Laura, Stratton, Richard, Ford, Dianne, O’Reilly, Steven
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754020/
https://ncbi.nlm.nih.gov/pubmed/33140521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16013
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