Light chain skewing in autoantibodies and B-cell receptors of the citrullinated antigen-binding B-cell response in rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting 1% of the world population. RA is associated with the presence of autoantibodies, of which anti-citrullinated protein antibodies (ACPA) are most prominent. ACPA are produced by citrullinated antigen-binding B cells that have presuma...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Slot, Linda M., Vergroesen, Rochelle D., Kerkman, Priscilla F., Staudinger, Ellen, Reijm, Sanne, van Dooren, Hugo J., van der Voort, Ellen I. H., Huizinga, Tom W. J., Toes, René E. M., Scherer, Hans U.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009422/
https://ncbi.nlm.nih.gov/pubmed/33784344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247847
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