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Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis
Autoreactive B cells mediate autoimmune pathology, but exactly how remains unknown. A hallmark of rheumatoid arthritis (RA), a common autoimmune disease, is the presence of disease-specific anticitrullinated protein antibodies (ACPAs). Here, we showed that ACPA-positive B cells in patients with RA s...
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| Publicado no: | Sci Transl Med |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7615909/ https://ncbi.nlm.nih.gov/pubmed/33208502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaz5327 |
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