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Deep neural networks identify sequence context features predictive of transcription factor binding
Transcription factors (TFs) bind DNA by recognizing specific sequence motifs, typically of length 6–12bp. A motif can occur many thousands of times in the human genome, but only a subset of those sites are actually bound. Here we present a machine learning framework leveraging existing convolutional...
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| Publicat a: | Nat Mach Intell |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8009085/ https://ncbi.nlm.nih.gov/pubmed/33796819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42256-020-00282-y |
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