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Deep neural networks identify sequence context features predictive of transcription factor binding
Transcription factors (TFs) bind DNA by recognizing specific sequence motifs, typically of length 6–12bp. A motif can occur many thousands of times in the human genome, but only a subset of those sites are actually bound. Here we present a machine learning framework leveraging existing convolutional...
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| Publicado no: | Nat Mach Intell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8009085/ https://ncbi.nlm.nih.gov/pubmed/33796819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42256-020-00282-y |
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