Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS

Zirconia nanoparticles (ZrO(2) NPs) are commonly used in the field of biomedical materials, but their antitumor activity and mechanism is unclear. Herein, we evaluated the anti-tumor activity of ZrO(2) NPs and explored the anti-tumor mechanism. The results of in vitro and in vivo experiments showed...

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Bibliographische Detailangaben
Veröffentlicht in:Front Chem
Hauptverfasser: Shang, Yinghui, Wang, Qinghai, Li, Jian, Liu, Haiting, Zhao, Qiangqiang, Huang, Xueyuan, Dong, Hang, Chen, Wansong, Gui, Rong, Nie, Xinmin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Chemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007972/
https://ncbi.nlm.nih.gov/pubmed/33796503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2021.522708
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