Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS

Zirconia nanoparticles (ZrO(2) NPs) are commonly used in the field of biomedical materials, but their antitumor activity and mechanism is unclear. Herein, we evaluated the anti-tumor activity of ZrO(2) NPs and explored the anti-tumor mechanism. The results of in vitro and in vivo experiments showed...

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Bibliografiske detaljer
Udgivet i:Front Chem
Main Authors: Shang, Yinghui, Wang, Qinghai, Li, Jian, Liu, Haiting, Zhao, Qiangqiang, Huang, Xueyuan, Dong, Hang, Chen, Wansong, Gui, Rong, Nie, Xinmin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007972/
https://ncbi.nlm.nih.gov/pubmed/33796503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2021.522708
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