Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS

Zirconia nanoparticles (ZrO(2) NPs) are commonly used in the field of biomedical materials, but their antitumor activity and mechanism is unclear. Herein, we evaluated the anti-tumor activity of ZrO(2) NPs and explored the anti-tumor mechanism. The results of in vitro and in vivo experiments showed...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Shang, Yinghui, Wang, Qinghai, Li, Jian, Liu, Haiting, Zhao, Qiangqiang, Huang, Xueyuan, Dong, Hang, Chen, Wansong, Gui, Rong, Nie, Xinmin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007972/
https://ncbi.nlm.nih.gov/pubmed/33796503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2021.522708
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