Structural and functional analysis of LIM domain-dependent recruitment of paxillin to αvβ3 integrin-positive focal adhesions

The LIM domain-dependent localization of the adapter protein paxillin to β3 integrin-positive focal adhesions (FAs) is not mechanistically understood. Here, by combining molecular biology, photoactivation and FA-isolation experiments, we demonstrate specific contributions of each LIM domain of paxil...

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Bibliographic Details
Published in:Commun Biol
Main Authors: Ripamonti, Marta, Liaudet, Nicolas, Azizi, Latifeh, Bouvard, Daniel, Hytönen, Vesa P., Wehrle-Haller, Bernhard
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007706/
https://ncbi.nlm.nih.gov/pubmed/33782527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01886-9
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