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Marching at the front and dragging behind: differential αVβ3-integrin turnover regulates focal adhesion behavior

Integrins are cell–substrate adhesion molecules that provide the essential link between the actin cytoskeleton and the extracellular matrix during cell migration. We have analyzed αVβ3-integrin dynamics in migrating cells using a green fluorescent protein–tagged β3-integrin chain. At the cell front,...

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Autors principals: Ballestrem, Christoph, Hinz, Boris, Imhof, Beat A., Wehrle-Haller, Bernhard
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199321/
https://ncbi.nlm.nih.gov/pubmed/11756480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200107107
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