Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study

BACKGROUND: We conducted a Mendelian randomisation (MR) study to investigate whether physical activity (PA) causes a reduction of colorectal cancer risk and to understand the contributions of effects mediated through changes in body fat. METHODS: Common genetic variants associated with self-reported...

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Bibliografske podrobnosti
izdano v:Br J Cancer
Main Authors: Zhang, Xiaomeng, Theodoratou, Evropi, Li, Xue, Farrington, Susan M., Law, Philip J., Broderick, Peter, Walker, Marion, Klimentidis, Yann C., Rees, Jessica M. B., Houlston, Richard S., Tomlinson, Ian P. M., Burgess, Stephen, Campbell, Harry, Dunlop, Malcolm G., Timofeeva, Maria
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007642/
https://ncbi.nlm.nih.gov/pubmed/33510439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01236-2
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