Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study

BACKGROUND: We conducted a Mendelian randomisation (MR) study to investigate whether physical activity (PA) causes a reduction of colorectal cancer risk and to understand the contributions of effects mediated through changes in body fat. METHODS: Common genetic variants associated with self-reported...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Zhang, Xiaomeng, Theodoratou, Evropi, Li, Xue, Farrington, Susan M., Law, Philip J., Broderick, Peter, Walker, Marion, Klimentidis, Yann C., Rees, Jessica M. B., Houlston, Richard S., Tomlinson, Ian P. M., Burgess, Stephen, Campbell, Harry, Dunlop, Malcolm G., Timofeeva, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007642/
https://ncbi.nlm.nih.gov/pubmed/33510439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01236-2
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