A food-responsive switch modulates TFEB and autophagy, and determines susceptibility to coxsackievirus infection and pancreatitis

Almost a billion people worldwide are chronically undernourished. Herein, using a mouse model of coxsackievirus B3 (CVB3) infection, we report that a single day of food restriction (FR) markedly increases susceptibility to attenuated enterovirus infection, replication, and disease. These “pro-viral”...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Alirezaei, Mehrdad, Flynn, Claudia T., Garcia, Selma D., Kimura, Taishi, Whitton, J. Lindsay
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007148/
https://ncbi.nlm.nih.gov/pubmed/32019403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1720425
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