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Pancreatic acinar cell-specific autophagy disruption reduces coxsackievirus replication and pathogenesis in vivo

Autophagy protects against many infections by inducing the lysosomal-mediated degradation of invading pathogens. However, previous in vitro studies suggest that some enteroviruses not only evade these protective effects, but also exploit autophagy to facilitate their replication. We generated Atg5(f...

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Sonraí Bibleagrafaíochta
Main Authors: Alirezaei, Mehrdad, Flynn, Claudia T., Wood, Malcolm R., Whitton, J. Lindsay
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308121/
https://ncbi.nlm.nih.gov/pubmed/22423969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.01.014
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