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Pancreatic acinar cell-specific autophagy disruption reduces coxsackievirus replication and pathogenesis in vivo

Autophagy protects against many infections by inducing the lysosomal-mediated degradation of invading pathogens. However, previous in vitro studies suggest that some enteroviruses not only evade these protective effects, but also exploit autophagy to facilitate their replication. We generated Atg5(f...

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Bibliografiske detaljer
Main Authors: Alirezaei, Mehrdad, Flynn, Claudia T., Wood, Malcolm R., Whitton, J. Lindsay
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308121/
https://ncbi.nlm.nih.gov/pubmed/22423969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.01.014
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