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Coxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo

RNA viruses modify intracellular membranes to produce replication scaffolds. In pancreatic cells, coxsackievirus B3 (CVB3) hijacks membranes from the autophagy pathway, and in vivo disruption of acinar cell autophagy dramatically delays CVB3 replication. This is reversed by expression of GFP-LC3, in...

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Bibliografske podrobnosti
izdano v:Autophagy
Main Authors: Alirezaei, Mehrdad, Flynn, Claudia T, Wood, Malcolm R, Harkins, Stephanie, Whitton, J Lindsay
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590631/
https://ncbi.nlm.nih.gov/pubmed/26090585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1063769
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