Coxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo

RNA viruses modify intracellular membranes to produce replication scaffolds. In pancreatic cells, coxsackievirus B3 (CVB3) hijacks membranes from the autophagy pathway, and in vivo disruption of acinar cell autophagy dramatically delays CVB3 replication. This is reversed by expression of GFP-LC3, in...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Alirezaei, Mehrdad, Flynn, Claudia T, Wood, Malcolm R, Harkins, Stephanie, Whitton, J Lindsay
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590631/
https://ncbi.nlm.nih.gov/pubmed/26090585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1063769
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