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Pancreatic acinar cell-specific autophagy disruption reduces coxsackievirus replication and pathogenesis in vivo
Autophagy protects against many infections by inducing the lysosomal-mediated degradation of invading pathogens. However, previous in vitro studies suggest that some enteroviruses not only evade these protective effects, but also exploit autophagy to facilitate their replication. We generated Atg5(f...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308121/ https://ncbi.nlm.nih.gov/pubmed/22423969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.01.014 |
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