Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer

Among more than 200 BAP1-mutant families affected by the “BAP1 cancer syndrome,” nearly all individuals inheriting a BAP1 mutant allele developed one or more malignancies during their lifetime, mostly uveal and cutaneous melanoma, mesothelioma, and clear-cell renal cell carcinoma. These cancer types...

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I publikationen:Cancer Discov
Huvudupphovsmän: Carbone, Michele, Harbour, J. William, Brugarolas, James, Bononi, Angela, Pagano, Ian, Dey, Anwesha, Krausz, Thomas, Pass, Harvey I., Yang, Haining, Gaudino, Giovanni
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006752/
https://ncbi.nlm.nih.gov/pubmed/32690542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-1220
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