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Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer
Among more than 200 BAP1-mutant families affected by the “BAP1 cancer syndrome,” nearly all individuals inheriting a BAP1 mutant allele developed one or more malignancies during their lifetime, mostly uveal and cutaneous melanoma, mesothelioma, and clear-cell renal cell carcinoma. These cancer types...
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| Vydáno v: | Cancer Discov |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8006752/ https://ncbi.nlm.nih.gov/pubmed/32690542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-1220 |
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