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Lysophosphatidylcholine acyltransferase 3 deficiency activates the Wnt/β-catenin pathway and thereby impairs adipogenesis in preadipocytes
Levels of polyunsaturated phosphatidylcholine (PC) influence plasma membrane structure and function. PC is synthesized de novo in the Kennedy pathway and then undergoes extensive deacylation/reacylation remodeling via Lands’ cycle (non-Kennedy pathway). The reacylation is catalyzed by lysophosphatid...
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| Publicado no: | Biochim Biophys Acta Mol Cell Biol Lipids |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8006744/ https://ncbi.nlm.nih.gov/pubmed/29673706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2018.04.008 |
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