Lysophosphatidylcholine Acyltransferase 3 Knockdown-mediated Liver Lysophosphatidylcholine Accumulation Promotes Very Low Density Lipoprotein Production by Enhancing Microsomal Triglyceride Transfer Protein Expression

After de novo biosynthesis phospholipids undergo extensive remodeling by the Lands' cycle. Enzymes involved in phospholipid biosynthesis have been studied extensively but not those involved in reacylation of lysophosphopholipids. One key enzyme in the Lands' cycle is fatty acyl-CoA:lysopho...

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Detalhes bibliográficos
Main Authors: Li, Zhiqiang, Ding, Tingbo, Pan, Xiaoyue, Li, Yan, Li, Ruohan, Sanders, Philip E., Kuo, Ming-Shang, Hussain, M. Mahmood, Cao, Guoqing, Jiang, Xian-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370195/
https://ncbi.nlm.nih.gov/pubmed/22511767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334664
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