Dact1, a Nutritionally Regulated Preadipocyte Gene, Controls Adipogenesis by Coordinating the Wnt/β-Catenin Signaling Network

OBJECTIVE—Wnt signaling inhibits adipogenesis, but its regulation, physiological relevance, and molecular effectors are poorly understood. Here, we identify the Wnt modulator Dapper1/Frodo1 (Dact1) as a new preadipocyte gene involved in the regulation of murine and human adipogenesis. RESEARCH DESIG...

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Main Authors: Lagathu, Claire, Christodoulides, Constantinos, Virtue, Sam, Cawthorn, William P., Franzin, Chiara, Kimber, Wendy A., Nora, Edoardo Dalla, Campbell, Mark, Medina-Gomez, Gema, Cheyette, Benjamin N.R., Vidal-Puig, Antonio J., Sethi, Jaswinder K.
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2009
主題:
Signal Transduction
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646059/
https://ncbi.nlm.nih.gov/pubmed/19073771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1180
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