Transcriptomic approach predicts a major role for transforming growth factor beta type 1 pathway in L-Dopa-induced dyskinesia in parkinsonian rats

Dyskinesia induced by long-term L-Dopa (LID) therapy in Parkinson disease is associated with altered striatal function whose molecular bases remain unclear. Here, a transcriptomic approach was applied for comprehensive analysis of distinctively regulated genes in striatal tissue, their specific path...

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Gepubliceerd in:Genes Brain Behav
Hoofdauteurs: Dyavar, Shetty Ravi, Potts, Lisa F., Beck, Goichi, Shetty, Bhagya Laxmi Dyavar, Lawson, Benton, Podany, Anthony T., Fletcher, Courtney V., Amara, Rama Rao, Papa, Stella M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006569/
https://ncbi.nlm.nih.gov/pubmed/32741046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12690
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