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The role of Notch ligand Jagged1 in osteosarcoma proliferation, metastasis, and recurrence

BACKGROUND: Osteosarcoma is the most common primary bone cancer occurring in young adults and the 5-year survival rate of patients with metastatic osteosarcoma is less than 30% due to high metastatic recurrence and drug resistance. Notch is a highly conserved cell to cell signaling pathway in evolut...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Orthop Surg Res
Hauptverfasser: Zhang, Jianping, Li, Na, Lu, Siyu, Chen, Yanling, Shan, Lequn, Zhao, Xingcheng, Xu, Yongqing
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006358/
https://ncbi.nlm.nih.gov/pubmed/33781318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-021-02372-y
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