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Low incidence of ABL-class and JAK-STAT signaling pathway alterations in uniformly treated pediatric and adult B-cell acute lymphoblastic leukemia patients using MRD risk-directed approach – a population-based study

BACKGROUND: ABL-class and JAK-STAT signaling pathway activating alterations have been associated with both a poor post-induction minimal residual disease (MRD) response and an inferior outcome in B-cell acute lymphoblastic leukemia (B-ALL). However, in most of the studies patients received non-unifo...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Norvilas, Rimvydas, Dirse, Vaidas, Semaskeviciene, Ruta, Mickeviciute, Orinta, Gineikiene, Egle, Stoskus, Mindaugas, Vaitkeviciene, Goda, Rascon, Jelena, Griskevicius, Laimonas
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006339/
https://ncbi.nlm.nih.gov/pubmed/33781217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07781-6
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