Therapeutic Plasma Exchange in Multiple Sclerosis Patients with Abolished Interferon-beta Bioavailability

BACKGROUND: Neutralizing antibodies (NAb) to interferon-beta (IFN-β) are associated with reduced bioactivity and efficacy of IFN-β in multiple sclerosis (MS). The myxovirus resistance protein A (MxA) gene expression is one of the most appropriate markers of biological activity of exogenous IFN-β. We...

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Udgivet i:Med Sci Monit
Main Authors: Giedraitiene, Natasa, Kaubrys, Gintaras, Kizlaitiene, Rasa, Bagdonatė, Loreta, Griskevicius, Laimonas, Valceckiene, Vilma, Stoskus, Mindaugas
Format: Artigo
Sprog:Inglês
Udgivet: International Scientific Literature, Inc. 2015
Fag:
Clinical Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456985/
https://ncbi.nlm.nih.gov/pubmed/26009248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.894119
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