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Deciphering the multifaceted roles of TET proteins in T-cell lineage specification and malignant transformation

TET proteins are DNA demethylases that can oxidize 5-methylcytosine (5mC) to generate 5- hydroxymethylcytosine (5hmC) and other oxidized mC bases (oxi-mCs). Importantly, TET proteins govern cell fate decisions during development of various cell types by activating a cell-specific gene expression pro...

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Detalles Bibliográficos
Publicado en:Immunol Rev
Autor principal: Tsagaratou, Ageliki
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005446/
https://ncbi.nlm.nih.gov/pubmed/33410200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12940
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