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TET Methylcytosine Oxidases in T Cell and B Cell Development and Function

DNA methylation is established by DNA methyltransferases and is a key epigenetic mark. Ten-eleven translocation (TET) proteins are enzymes that oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) and further oxidization products (oxi-mCs), which indirectly promote DNA demethylation. Her...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Tsagaratou, Ageliki, Lio, Chan-Wang J., Yue, Xiaojing, Rao, Anjana
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374156/
https://ncbi.nlm.nih.gov/pubmed/28408905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00220
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