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TET family proteins and their role in stem cell differentiation and transformation

One of the main regulators of gene expression during embryonegesis and stem cell differentiation is DNA methylation. The recent identification of hydroxymethylcytosine (5hmC) as a novel epigenetic mark sparked an intense effort to characterize its specialized enzymatic machinery and to understand th...

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Detalhes bibliográficos
Main Authors: Cimmino, Luisa, Abdel-Wahab, Omar, Levine, Ross L., Aifantis, Iannis
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244690/
https://ncbi.nlm.nih.gov/pubmed/21885017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.08.007
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