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Affibody-Derived Drug Conjugates Targeting HER2: Effect of Drug Load on Cytotoxicity and Biodistribution

Affibody molecules hold great promise as carriers of cytotoxic drugs for cancer therapy due to their typically high affinity, easy production, and inherent control of the drug molecules’ loading and spatial arrangement. Here, the impact of increasing the drug load from one to three on the properties...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pharmaceutics
Egile Nagusiak: Ding, Haozhong, Xu, Tianqi, Zhang, Jie, Tolmachev, Vladimir, Oroujeni, Maryam, Orlova, Anna, Gräslund, Torbjörn, Vorobyeva, Anzhelika
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005000/
https://ncbi.nlm.nih.gov/pubmed/33806887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13030430
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