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Cleavage of the Perlecan-Semaphorin 3A-Plexin A1-Neuropilin-1 (PSPN) Complex by Matrix Metalloproteinase 7/Matrilysin Triggers Prostate Cancer Cell Dyscohesion and Migration

The Perlecan-Semaphorin 3A-Plexin A1-Neuropilin-1 (PSPN) Complex at the cell surface of prostate cancer (PCa) cells influences cell–cell cohesion and dyscohesion. We investigated matrix metalloproteinase-7/matrilysin (MMP-7)’s ability to digest components of the PSPN Complex in bone metastatic PCa c...

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Publicat a:Int J Mol Sci
Autors principals: Tellman, Tristen V., Cruz, Lissette A., Grindel, Brian J., Farach-Carson, Mary C.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004947/
https://ncbi.nlm.nih.gov/pubmed/33809984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22063218
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